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guadinomine B biosynthesis

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
(2S,3S,7R)-2,3-diamino-8-(1-carbamoyl-2-iminoimidazolidin-4-yl)-7-hydroxyoctanoate + Ala-Val <=> 6-dehydroguadinomine_B + H2O + H+ not assigned

L-arginine + glycine <=> L-ornithine + Guanidinoacetate 2.1.4.1 glycine amidinotransferase

Carbamoyl_phosphate + (2S,3S,7R)-2-amino-3-amino-7-hydroxy-8-(2-iminoimidazolidin-4-yl)octanoate <=> (2S,3S,7R)-2,3-diamino-8-(1-carbamoyl-2-iminoimidazolidin-4-yl)-7-hydroxyoctanoate + phosphate 2.1.3

guanidinoacetyl-[polyketide_synthase] + aminomalonyl-[L-seryl-carrier_protein] + malonyl-CoA + L-glutamate + NADPH + H+ <=> (2S,3S,7R)-2-amino-3-amino-7-hydroxy-8-(2-iminoimidazolidin-4-yl)octanoyl-[GdnH_polyketide_synthase] + CoA + 2-oxoglutarate + holo-[L-seryl-carrier_protein] + CO2 + H2O + NADP+ 2.3.1

6-dehydroguadinomine_B + 2-oxoglutarate + O2 <=> guadinomine_B + succinate + CO2 1.14.11.M1

HCO3- + ATP <=> O-Carboxylphosphate + ADP 6.3.4.16 carbamoyl-phosphate synthase (ammonia)
6.3.5.5 carbamoyl-phosphate synthase (glutamine-hydrolysing)


O-Carboxylphosphate + NH3 <=> Carbamate + phosphate + H+ 6.3.4.16 carbamoyl-phosphate synthase (ammonia)
6.3.5.5 carbamoyl-phosphate synthase (glutamine-hydrolysing)


L-seryl-[L-seryl-carrier_protein] + NAD+ <=> 2-aminomalonyl_semialdehyde-[L-seryl-carrier_protein] + NADH + H+ 1.1.1

Guanidinoacetate + polyketide-[acp] + ATP <=> guanidinoacetyl-[polyketide_synthase] + AMP + diphosphate 6.2.1

Carbamate + ATP <=> Carbamoyl_phosphate + ADP 2.7.2.2 carbamate kinase
6.3.4.14 biotin carboxylase
6.3.4.16 carbamoyl-phosphate synthase (ammonia)
6.3.5.5 carbamoyl-phosphate synthase (glutamine-hydrolysing)




2-aminomalonyl_semialdehyde-[L-seryl-carrier_protein] + H2O + FAD <=> aminomalonyl-[L-seryl-carrier_protein] + FADH2 1.2.98

holo-[L-seryl-carrier_protein] + L-serine + ATP <=> L-seryl-[L-seryl-carrier_protein] + AMP + diphosphate 6.2.1.ae

(2S,3S,7R)-2-amino-3-amino-7-hydroxy-8-(2-iminoimidazolidin-4-yl)octanoyl-[GdnH_polyketide_synthase] + H2O <=> (2S,3S,7R)-2-amino-3-amino-7-hydroxy-8-(2-iminoimidazolidin-4-yl)octanoate + [GdnH_polyketide_synthase/acyl-carrier_protein] + H+ not assigned

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